LATEST ON BIO-INKJET PRINTERS

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LATEST ON BIO-INKJET PRINTERS

 user 2006-12-20 at 1:47:00 pm Views: 67
  • #17239

    Bio-Inkjet Printer Draws Muscle and Bone
    There
    are many things we’ve come to expect from our computer printers:
    photos, letters, greeting cards, maybe even glowing wallpaper someday.
    But muscle and bone? You wouldn’t have gone there until this week, when
    scientists at Carnegie Mellon announced they have developed a printer
    that outputs in “bio-ink”—a format they hope will pave the way for
    important organization and growth of stem cells.In development for the
    past eight years, the printer is similar to a conventional ink jet, but
    with a custom-built nozzle designed to print patterns more accurately.
    The machine prints in bio-ink, solutions of hormones that alter cell
    behavior,  to create a blueprint for cells to grow and differentiate
    into the various types that scientists want to create, according to Dr.
    Julie A. Phillippi. She has worked on the project for about a year and
    a half.“We loaded the bio-inks and  then printed square patterns of the
    bone bio-ink on a glass slide,” says Phillippi. “Then we placed the
    slide with the patterns in a dish with muscle-derived stem cells from
    adult mice. The cells growing on the bone bio-ink pattern began to
    exhibit characteristics of bone-like cells, and cells outside the
    pattern began to look like muscle cells.”The scientists use a software
    program, designed in-house, to create the patterns. “The inkjet is
    ideal for what we’re trying to do because it allows for precise control
    over size, shape and concentration of the bio-ink patterns,” says
    Phillippi. The team is currently developing a 3D printer that consists
    of multiple print heads and delivers gel-like proteins as well as
    growth factors to build 3D patterns layer-by-layer.The printed bio-ink
    patterns have applications in tissue regeneration, Phillippi insists,
    including using adult stem cells to treat tissue defects. “Through such
    a patterning approach, our vision is to heal patients with defects that
    span multiple tissue types using the patient’s own stem cells,” she
    says.