*NEWS* BLOOD VESSELS FROM INKJET PRINTER

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Date: Tuesday September 4, 2007 11:34:00 am
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    Researchers Print Blood Vessels from Ink Jet Printer
    Japanese researchers have devised a way to print new blood vessels from an ink jet printer
    Doctors
    performing artery bypass surgery replace clogged arteries with veins
    from the inner thigh of the same patient.  This vein, the great
    saphenous vein, is the longest in the human body and can easily be
    removed if a patient needs a bypass.However, this approach has its
    limitations.  The patient must have good collateral blood flow and the
    very long incision can run nearly the entire length of the leg. Ask a
    few post operation bypass patients and many of them will tell you that
    the pain from the removal of the great saphenous is often worse than
    the heart surgery itself.Researchers from Tokyo Medical and Dental
    University and Kanagawa Academy of Science and Technology have some
    promising research that could make the removal of the great saphenous
    vein unnecessary in future coronary artery bypass operations.The
    technology they are developing allows them to print new blood vessels
    and capillaries from an ink jet printer. The ink used in the technology
    is made from artificial cells and medical gel in a solution of calcium
    chloride. This ink solidifies into a tube with a lining of endothelial
    cells and an outer case of smooth muscle cells.The technology isn’t
    mature enough yet to replace the veins from a patients own body with
    researchers only being able to create a prototype vessel with an inner
    diameter of 1 mm and a length of 1 cm. The prototype isn’t strong
    enough to support blood flow yet either. Tech.co.uk says that once the
    technology is more mature and robust there is no reason why scientists
    can’t build up artificial organs from layered, printed sheets using the
    technology.The process used in this research is very similar to the
    research being carried out to help combat diseases like Duchenne
    Muscular Dystrophy and other autoimmune disease by Carnegie Melon’s
    Institute for Complex engineering Systems and the Carnegie Mellon
    Robotics Institute.This research was aimed at using ink-jet printing
    technology to print out muscle and bone cells and uses Stem cells as a
    component of their ink. The printer developed in the Carnegie Mellon
    research deposited and immobilized growth factors in virtually any
    design, pattern or concentration. The patterns were laid down on
    extracellular matrix-coated slides. The slides were topped with
    muscle-derived stem cells and directed differentiate into different
    pathways to make bone or muscle.

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